Fisher, D.G., K.A. Sharifi, I.M. Shah, C.M. Gorick, V.B., A.C. Debski, M.R. Hoch, T. Cruz, J.D. Samuels, D. Schlesinger, J. Sheehan, D. Moore, J.R. Lukens, G.W. Miller, P. Tvrdik, and R.J. Price (2024) Focused Ultrasound Blood-Brain Barrier Opening Arrests the Growth and Formation of Cerebral Cavernous Malformations. bioRxiv. DOI: PMID: 38352349.

Thim, E.A., L.E. Petricca, F. Rivera-Escalera, A.S. Mathew, M.R. Elliot, T.N.J Bullock, and R.J. Price (2024) Boiling Histotripsy Monotherapy Yields Abscopal Melanoma Control and Drives Dendritic Cell Activation and Acquisition of Tumor Antigen. Theranostics. DOI: 10.7150/thno.92089. PMID: 38389838.

Samuels, J.D., J.R. Lukens, and R.J. Price (2023) Emerging Roles for ITAM and ITIM Receptor Signaling in Microglial Biology and Alzheimer’s Disease-Related Amyloidosis. Journal of Neurochemistry. doi: 10.1111/jnc.15981. PMID: 37822118.

Fisher, D.G., K.A. Sharifi, E.Z. Ulutas, J.S. Kumar, M.Y.S. Kalani, G.W. Miller, R.J. Price, P. Tvrdik (2023) MRI of Mouse Cerebral Cavernomas Reveals Differential Lesion Progression and Variable Permeability to Gadolinium. Arterioscler Thromb Vasc Biol. doi: 10.1161/ATVBAHA.122.318938. PMID: 37078284

Samuels, J.D., K.A. Moore, H.E. Ennerfelt, A.M. Johnson, A.E. Walsh, R.J. Price, and J.R. Lukens (2023) The Alzheimer’s Disease Risk Factor INPP5D Restricts Neuroprotective Microglial Responses in Amyloid Beta-Mediated Pathology. Alzheimers. Dement. DOI: 10.1002/alz.13089. PMID: 37061460

Thim, E.A., T. Fox, T. Deering, M. Kester, and R.J. Price (2023) Treating Solid Tumors via Augmentation of Bioactive C6 Ceramide Levels with Thermally Ablative Focused Ultrasound. Drug Deliv. Transl. Res. PMID: 37335416

Gorick, C.M., V.R. Breza, K.M. Nowak, V.W.T. Cheng, D.G. Fisher, A.C. Debski, M.R. Hoch, Z.E.F. Demir, N.M. Tran, M.R. Schwartz, N.D. Sheybani, and R.J. Price (2022) Applications of Focused Ultrasound-Mediated Drug and Gene Delivery Across the Blood-Brain Barrier. Advanced Drug Delivery Reviews. DOI: PMID: 36272635

Nowak, K.M., M.R. Schwartz, V.R. Breza, and R.J. Price (2022) Sonodynamic Therapy: Rapid Progress and New Opportunities for Non-Invasive Tumor Cell Killing with Sound. Cancer Letters. DOI: 10.1016/j.canlet.2022.215592. PMID: 35151824

Gorick, C.M., J.J. Saucerman, and R.J. Price (2022) Computational Model of Brain Endothelial Cell Signaling Pathways Predicts Therapeutic Targets for Cerebral Pathologies. J Mol Cell Cardiol. DOI: PMID: 34798125

Sheybani, N.D., A.R. Witter, W.J. Garrison, G.W. Miller, R.J. Price, T.N.J. Bullock (2021) Profiling of the Immune Landscape in Murine Glioblastoma following Blood Brain/Tumor Barrier Disruption with MR Image-guided Focused Ultrasound. J Neurooncol. DOI: 10.1007/s11060-021-03887-4. PMID: 34734364.

Schwartz, M.R., A.C. Debski, and R.J. Price (2021) Ultrasound-Targeted Nucleic Acid Delivery to Solid Tumors. J Cont Rel. DOI: 10.1016/j.jconrel.2021.10.010. PMID: 34655678.

Clark, R.A., Z.G. Garman, R.J. Price, and N.D. Sheybani (2021) Functional Intersections Between Extracellular Vesicles and Oncolytic Therapies. Trends Pharmacol Sci. DOI: 10.1016/ PMID: 34598797

Mathew, A.S., C.M. Gorick, and R.J. Price (2021) Multiple Regression Analysis of a Comprehensive Transcriptomic Data Assembly Elucidates Mechanically- and Biochemically-Driven Gene Sets in Response to Focused Ultrasound Blood-Brain Barrier Disruption. Theranostics. DOI: 10.7150/thno.65064. PMID: 34815790.

Mathew, A.S., C.M. Gorick, and R.J. Price (2021) Single Cell Mapping of Focused Ultrasound Transfected Brain. Gene Therapy. DOI: 10.1038/s41434-021-00226-0. PMID: 33526842.

Sheybani, N.D., V.R. Breza, S. Paul, K.S. McCauley, S.S. Berr, G.W. Miller, K.D. Neumann, and R.J. Price (2021) ImmunoPET-Informed Sequence for Focused Ultrasound-Targeted mCD47 Blockade Controls Glioma. J Control Release. DOI:10.1016/j.jconrel.2021.01.023. PMID: 33476735

Mathew, A.S., C.M. Gorick, E.A. Thim, W.J. Garrison, A.L. Klibanov, G.W. Miller, N.D. Sheybani, and R.J. Price (2020) Transcriptomic Response of Brain Tissue to Focused Ultrasound-Mediated Blood-Brain Barrier Disruption Depends Strongly on Anesthesia. Bioengineering & Transla Med. DOI: 10.1002/btm2.10198. PMID: 34027087.

§Sheybani, N.D., §A.R. Witter, E.A. Thim, T.N.J. Bullock, and R.J. Price (2020) Combination of Thermally Ablative Focused Ultrasound With Gemcitabine Controls Breast Cancer via Adaptive Immunity. J Immunother Cancer. 8:e001008. PMID: 32819975

Sheybani, N.D., A.J. Batts, A.S. Mathew, E.A. Thim, and R.J. Price (2020)  Focused Ultrasound Hyperthermia Augments Release of Glioma-Derived Extracellular Vesicles with Differential Immunomodulatory Capacity. Theranostics. 10:7436-7447. PMID: 32642004

Gorick, C.M., A.S. Mathew, W.J. Garrison, E.A. Thim, D.G. Fisher, C.A. Copeland, J. Song, G.W. Miller, A.L. Klibanov, and R.J. Price (2020) Sonoselective Transfection of Cerebral Microvasculature Without Blood-Brain Barrier Disruption. Proc Nat Acad Sci. 117(11):5644-5654. PMID: 32123081

§Curley, C.T., §B.P. Mead, K. Negron, N. Kim, W.J. Garrison, E.A. Thim, K.M. Kingsmore, J.M. Munson, G.W. Miller, A.L.Klibanov, J.S. Suk, J. Hanes, and R.J. Price (2020) Augmentation of Brain Tumor Interstitial Flow via Focused Ultrasound Promotes Brain-Penetrating Nanoparticle Dispersion and Transfection. Science Advances. 6:aay1344. DOI: 10.1126/sciadv.aay1344. PMID: 32494662

Curley, C.T., A.D. Stevens, A.S. Mathew, K. Stasiak, W.J. Garrison, G.W. Miller, N.D. Sheybani, V.H. Engelhard, T.N.J. Bullock, and R.J. Price (2020) Immunomodulation of Intracranial Melanoma in Response to Blood-Tumor Barrier Opening with Focused Ultrasound. Theranostics. 10:8821-8833. PMID: 32754281

Norat, P., S. Soldozy, J.D. Sokolowski, C.M. Gorick, J.S. Kumar, Y. Chae, K. Yagmurlu, F. Prada, M. Walker, M.R. Levitt, R.J. Price, P. Tvrdik, and M.Y.S. Kalani (2020) Mitochondrial Dysfunction in Neurological Disorders: Exploring Mitochondrial Transplantation. npj Regenerative Medicine. DOI: 10.1038/s41536-020-00107-x. PMID: 33298971

§Mead, B.P., §C.T. Curley, N. Kim, K. Negron, W.J. Garrison, J. Song, D. Rao, G. Wilson Miller, J.W. Mandell, B.J. Purow, J.S. Suk, J. Hanes, and R.J. Price (2019) Focused Ultrasound Pre-Conditioning for Augmented Nanoparticle Penetration and Efficacy in the Central Nervous System. Small. 15(49):e1903460. PMID: 31642183.

Sheybani N.D. and R.J. Price (2019) Perspectives on Recent Progress in Focused Ultrasound Immunotherapy. Theranostics. 9: 7749-7758. DOI:10.7150/thno.37131. PMID: 31695798.

Price, R.J., D.G. Fisher, J.S. Suk, J. Hanes, H.S. Ko, and J.H. Kordower (2019) Parkinson’s Disease Gene Therapy: Will Focused Ultrasound and Nanovectors be the Next Frontier? Movement Disorders. DOI: 10.1002/mds.27675. PMID: 30908781.

Fisher, D.G., and R.J. Price (2019) Recent Advances in the Use of Focused Ultrasound for MR Image-Guided Nanoparticle Delivery to the Central Nervous System. Frontiers in Pharmacology. 10:1348. DOI: 10.3389/fphar.2019.01348. PMID: 31798453.

Heuslein, J.L., C.M. Gorick, and R.J. Price (2019) Epigenetic Regulators of the Revascularization Response to Chronic Arterial Occlusion. Cardiovascular Research. 115:701-712. DOI:10.1093/cvr/cvz001. PMID: 30629133.

Heuslein, J.L., C.M. Gorick, S.P. McDonnell, J. Song, B.H. Annex, and R.J. Price (2018) Exposure of Endothelium to Biomimetic Flow Waveforms Yields Identification of miR-199a as a Potent Regulator of Arteriogenesis. Molecular Therapy: Nucleic Acids. 12:829-844. DOI:10.1016/j.omtn.2018.08.001. PMID: 30153567.

Gorick, C.M., N.D. Sheybani, C.T. Curley, and R.J. Price (2018) Listening in on the Microbubble Crowd: Advanced Acoustic Monitoring for Improved Control of Blood-Brain Barrier Opening with Focused Ultrasound. Theranostics. 8:2988-2991. DOI:10.7150/thno.26025. PMID: 29897053.

Heuslein, J.L., S.P. McDonnell, J. Song, B.H. Annex and R.J. Price (2018) MicroRNA-146a Regulates Perfusion Recovery in Response to Arterial Occlusion via Arteriogenesis. Front. Bioeng. Biotechnol. DOI: 10.3389/fbioe.2018.00001. PMID: 29404323.

Heuslein, J.L., C.M. Gorick, J. Song, and R.J. Price (2017) DNA Methyltransferase 1–Dependent DNA Hypermethylation Constrains Arteriogenesis by Augmenting Shear Stress Set Point. J Am Heart Assoc. 6:e007673. DOI: 10.1161/JAHA.117.007673. PMID: 29191807.

Mead, B.P., N. Kim, G.W. Miller, D. Hodges, P. Mastorakos, A.L Klibanov, J.W. Mandell, J. Hirsh, J.S. Suk, J. Hanes, and R.J. Price (2017) Novel Focused Ultrasound Gene Therapy Approach Non-Invasively Restores Dopaminergic Neuron Function in a Rat Parkinson’s Disease Model. Nano Lett. 17:3533-3542. DOI: 10.1021/acs.nanolett.7b00616. PMID: 28511006.

Dallapiazza, R.F., K.F. Timbie, S. Holmberg, J. Gatesman, M.B. Lopes, R.J. Price, G.W. Miller, and W.J. Elias (2017) Noninvasive Neuromodulation and Thalamic Mapping with Low-Intensity Focused Ultrasound. J Neurosurgery. DOI: 10.3171/2016.11.JNS16976. PMID: 28430035.

Timbie, K.F., U. Afzal, A. Date, C. Zhang, J. Song, G.W. Miller, J.S. Suk, J. Hanes, and R.J. Price (2017) MR Image-Guided Delivery of Cisplatin-Loaded Brain-Penetrating Nanoparticles to Invasive Glioma with Focused Ultrasound. J Control Release. 263:120-131. DOI: 10.1016/j.jconrel.2017.03.017. PMID: 28288892.

§Curley, C.T., §N.D. Sheybani, T.N. Bullock, and R.J. Price (2017) Focused Ultrasound Immunotherapy for Central Nervous System Pathologies: Challenges and Opportunities. Theranostics. 7:3608-3623. DOI:10.7150/thno.21225.§Authors contributed equally. PMID: 29109764.

 Mead, B.P., P. Mastorakos, J.S. Suk, A.L. Klibanov, J. Hanes, and R.J. Price (2016) Targeted Gene Transfer to the Brain via the Delivery of Brain-Penetrating DNA Nanoparticles with Focused Ultrasound. J Control Release. 223: 109-117. PMID: 26732553.

§Timbie, K.F., §B.P. Mead, and R.J. Price (2015) Drug and Gene Delivery Across the Blood-Brain Barrier with Focused Ultrasound. J Control Release. 219:61-75. §Authors contributed equally. PMID: 26362698.

§Heuslein, J.L., §J.K. Meisner, R. J. Leiphart, X. Li, J. Song, H. Vincentelli, E.G. Ames, B.R. Blackman, and R.J. Price (2015) Mechanisms of Amplified Arteriogenesis in Collateral Artery Segments Exposed to Reversed Flow Direction. Arterioscler Thromb & Vasc Biol. 35: 2354-2365. §Authors contributed equally. PMID: 26338297.               

Meisner, J.K., B.H. Annex, and R.J. Price (2015) Despite Normal Arteriogenic and Angiogenic Responses, Hind Limb Perfusion Recovery and Necrotic and Fibroadipose Tissue Clearance are Impaired in Matrix Metalloproteinase 9-Deficient Mice. J Vasc Surg. S0741-5214(14)00138-4. PMID: 24582703.

§E. Nance, §K.F. Timbie, G.W. Miller, J. Song, C. Louttit, A.L. Klibanov, T-Y Shih, G. Swaminathan, G. Woodworth, J. Hanes and R.J. Price (2014) Noninvasive Delivery of Stealth Brain Penetrating Nanoparticles Across the Blood-Brain Barrier with MR Image-Guided Focused Ultrasound. J Control Release. 189:123-132. §Authors contributed equally. PMID: 24979210.

Burke, C.W., K. Timbie, E. Alexander IV, A.L. Klibanov, J.P. Sheehan, and R.J. Price (2014) Ultrasound-Activated Agents Comprised of 5FU-Bearing Nanoparticles Bonded to Microbubbles Inhibit Solid Tumor Growth and Improve Survival. Molecular Therapy. 22:321-8. PMID: 24172867.

Meisner, J.K., J. Song, B.H. Annex, and R.J. Price (2013). Myoglobin Overexpression Inhibits Reperfusion in the Ischemic Mouse Hindlimb Through lmpaired Angiogenesis but Not Arteriogenesis. Am J Pathol. 183:1710-8. PMID: 24095922.

Burke, C.W., J.S. Suk, A. Kim, Y-H. Hsiang, A.L. Klibanov, J. Hanes, and R.J. Price (2012) Markedly Enhanced Skeletal Muscle Transfection Achieved by the Ultrasound-Targeted Delivery of Non-Viral Gene Nanocarriers with Microbubbles. J Control Release. 162:414-421. PMID: 22800583.

Meisner, J.K., S. Sumer, K. Murrell, T. Higgins, and R.J. Price (2012) Laser Speckle Flowmetry Method for Measuring Spatial and Temporal Hemodynamic Alterations Throughout Large Microvascular Networks. Microcirculation. 19:619-631. PMID: 22591575.

Burke, C.W., Y-H. Hsiang, E. Alexander IV, A.L. Klibanov, and R.J. Price (2011) Covalently Linking Poly(Lactic-co-Glycolic Acid) Nanoparticles to Microbubbles Before Intravenous Injection Improves Their Ultrasound-Targeted Delivery to Skeletal Muscle. Small. 7: 1227-1235. PMID: 21456081.

Burke, C.W., A.L. Klibanov, J.P. Sheehan, and R.J. Price (2011) Inhibition of Glioma Growth by Microbubble Activation in a Subcutaneous Model Using Low Duty Cycle Ultrasound Without Significant Heating. J Neurosurg. 114:1654-1661. PMID: 21214331.

Nickerson, M.M., C.W. Burke, J.K. Meisner, C.W. Shuptrine, J. Song, and R.J. Price (2009) Capillary Arterialization Requires the Bone Marrow-Derived Cell (BMC)-Specific Expression of Chemokine (C-C motif) Receptor-2 (CCR2), but BMCs Do Not Transdifferentiate into Microvascular Smooth Muscle. Angiogenesis. 12:355-363. PMID: 19777360.

Nickerson, M.M., J. Song, J.K. Meisner, S. Bajikar, C.W. Burke, C.W. Shuptrine, G.K. Owens, T.C. Skalak, and R.J. Price (2009) Bone Marrow-Derived Cell-Specific Chemokine (C-C motif) Receptor-2 Expression is Required for Arteriolar Remodeling. Arterioscl Throm Vasc Biol. 29:1794-1801. PMID: 19734197.

Chappell, J.C., J. Song, A.L. Klibanov, and R.J. Price (2008) Ultrasonic Microbubble Destruction Stimulates Therapeutic Arteriogenesis via the CD18 Dependent Recruitment of Bone Marrow-Derived Cells. Arterioscl Throm Vasc Biol. 28:1117-1122. PMID: 18403725.

Chappell J.C., J. Song, C.W. Burke, A.L. Klibanov, and R.J. Price (2008) Targeted Delivery of Nanoparticles Bearing FGF-2 by Ultrasonic Microbubble Destruction for Therapeutic Arteriogenesis. Small. 4:1769-1777. PMID: 18720443.

Van Gieson, E.J., W.L. Murfee, T.C. Skalak, and R.J. Price (2003) Enhanced Spatial Smooth Muscle Cell Coverage of Microvessels Exposed to Increased Hemodynamic Stresses In Vivo. Circ Res. 92:929-936. PMID: 12663481.

Song, J., J.C. Chappell, M. Qi, E.J. Van Gieson, S. Kaul, and R.J. Price (2002) Influence of Injection Site, Microvascular Pressure, and Ultrasound Variables on Microbubble Mediated Delivery of Microspheres to Muscle. J Am Coll Cardiol. 39: 726-731.  PMID: 11849875.

Song, J., M. Qi, S. Kaul, and R.J. Price (2002) Stimulation of Arteriogenesis in Skeletal Muscle by Microbubble Destruction with Ultrasound. Circulation. 106:1550-1555. PMID: 12234963.

Skyba, D.M., R.J. Price, T.C. Skalak, and S. Kaul (1998) Direct In-vivo Visualization of Intravascular Destruction of Microbubbles by Ultrasound and its Local Effects on Tissue. Circulation. 98:290-293. PMID: 9711932.

Price, R.J., D.M. Skyba, S. Kaul, and T.C. Skalak (1998) Delivery of Colloidal Particles and Red Blood Cells to Tissue Through Microvessel Ruptures Created by Targeted Microbubble Destruction with Ultrasound. Circulation. 98:1264-1267. PMID: 9751673.

Price, R.J., G.K. Owens, and T.C. Skalak (1994) Immunohistochemical Identification of Arteriolar Development Using Markers of Smooth Muscle Differentiation: Evidence that Capillary Arterialization Proceeds from Terminal Arterioles. Circ Res. 75:520-527. PMID: 8062425.